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1

An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G-Quadruplex Topologies

Dr. Florian Hamon, Eric Largy, Aurore Guédin-Beaurepaire, Dr. Myriam Rouchon-Dagois, Assitan Sidibe, Dr. David Monchaud, Dr. Jean-Louis Mergny, Prof. Jean-Francois Riou, Dr. Chi-Hung Nguyen, Dr. Marie

Journal:

Angewandte Chemie

Year:

2011

Language:

english

File:

PDF, 425 KB

english, 2011

2

Highly Efficient G-Quadruplex Recognition by Bisquinolinium Compounds

De Cian, Anne, DeLemos, Elsa, Mergny, Jean-Louis, Teulade-Fichou, Marie-Paule, Monchaud, David

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 100 KB

english, 2007

3

DNA nanomachines and nanostructures involving quadruplexes

Alberti, Patrizia, Bourdoncle, Anne, Sacc?, Barbara, Lacroix, Laurent, Mergny, Jean-Louis

Journal:

Organic & Biomolecular Chemistry

Year:

2006

Language:

english

File:

PDF, 295 KB

english, 2006

4

Chemical Modification of Pyrimidine TFOs: Effect on i-Motif and Triple Helix Formation

Laurent Lacroix, Jean-Louis Mergny

Journal:

Archives of Biochemistry and Biophysics

Year:

2000

Language:

english

File:

PDF, 180 KB

english, 2000

5

The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes

Bertrand, Hélène, Monchaud, David, De Cian, Anne, Guillot, Régis, Mergny, Jean-Louis, Teulade-Fichou, Marie-Paule

Journal:

Organic & Biomolecular Chemistry

Year:

2007

Language:

english

File:

PDF, 280 KB

english, 2007

6

Analysis of Thermal Melting Curves

Mergny, Jean-Louis, Lacroix, Laurent

Journal:

Oligonucleotides

Year:

2003

Language:

english

File:

PDF, 930 KB

english, 2003

7

Orienting Tetramolecular G-Quadruplex Formation: The Quest for the Elusive RNA Antiparallel Quadruplex

Mendoza, Oscar, Porrini, Massimiliano, Salgado, Gilmar F., Gabelica, Valérie, Mergny, Jean-Louis

Journal:

Chemistry - A European Journal

Year:

2015

Language:

english

File:

PDF, 2.05 MB

english, 2015

8

Fluorescence energy transfer as a probe for nucleic acid structures and sequences

Mergny, Jean-Louis, Boutorine, Alexandre S., Garestier, Thérèse, Belloc, Francis, Rougée, Michel, Bulychev, N.V., Koshkin, A.A., Bourson, Jean, Lebedev, Alexandre V., Valeur, Bernard, Thuong, Nguyen T

Journal:

Nucleic Acids Research

Year:

1994

Language:

english

File:

PDF, 2.16 MB

english, 1994

9

Unusual DNA Conformations: Implications for Telomeres

Mills, Martin, Lacroix, Laurent, Arimondo, Paola, Leroy, Jean-Louis, Francois, Jean-Christophe, Klump, Horst, Mergny, Jean-Louis

Journal:

Current Medicinal Chemistry - Anti-Cancer Agents

Year:

2002

Language:

english

File:

PDF, 370 KB

english, 2002

10

Investigation of the interactions between Pt(II) and Pd(II) derivatives of 5,10,15,20-tetrakis (N-methyl-4-pyridyl) porphyrin and G-quadruplex DNA

Sabharwal, Navin C., Mendoza, Oscar, Nicoludis, John M., Ruan, Thomas, Mergny, Jean-Louis, Yatsunyk, Liliya A.

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2016

Language:

english

File:

PDF, 1.17 MB

english, 2016

11

Structural dynamics of propeller loop: towards folding of RNA G-quadruplex

Havrila, Marek, Stadlbauer, Petr, Kührová, Petra, Banáš, Pavel, Mergny, Jean-Louis, Otyepka, Michal, Šponer, Jiří

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 3.93 MB

english, 2018

12

Loop permutation affects the topology and stability of G-quadruplexes

Cheng, Mingpan, Cheng, Yu, Hao, Jingya, Jia, Guoqing, Zhou, Jun, Mergny, Jean-Louis, Li, Can

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 3.05 MB

english, 2018

13

DNA Quadruple Helices in Nanotechnology

Mergny, Jean-Louis, Sen, Dipankar

Journal:

Chemical Reviews

Year:

2019

Language:

english

File:

PDF, 4.34 MB

english, 2019

14

Characterization of G-Quadruplex Motifs in espB, espK, and cyp51 Genes of Mycobacterium tuberculosis as Potential Drug Targets

Mishra, Subodh Kumar, Shankar, Uma, Jain, Neha, Sikri, Kriti, Tyagi, Jaya Sivaswami, Sharma, Tarun Kumar, Mergny, Jean-Louis, Kumar, Amit

Journal:

Molecular Therapy — Nucleic Acids

Year:

2019

Language:

english

File:

PDF, 1.75 MB

english, 2019

15

Meeting report: Seventh International Meeting on Quadruplex Nucleic Acids (Changchun, P.R. China, September 6–9, 2019)

Mergny, Jean-Louis

Journal:

Year:

2020

Language:

english

File:

PDF, 9.70 MB

english, 2020

16

Composite 5-methylations of cytosines modulate i-motif stability in a sequence-specific manner: Implications for DNA nanotechnology and epigenetic regulation of plant telomeric DNA

Å kolÃ¡kovÃ¡, Petra, Badri, Zahra, FoldynovÃ¡-TrantÃrkovÃ¡, Silvie, RyneÅ¡, Jan, Å poner, JiÅÃ, FojtovÃ¡, Miloslava, Fajkus, JiÅÃ, Marek, Radek, VorlÃÄkovÃ¡, Michaela, Mergny, Jean-Louis, Trant

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2020

File:

PDF, 6.43 MB

2020

17

Correction to DNA Quadruple Helices in Nanotechnology

Mergny, Jean-Louis, Sen, Dipankar

Journal:

Chemical Reviews

Year:

2020

File:

PDF, 574 KB

2020

18

Fluorescence Resonance Energy Transfer as a Probe for G-Quartet Formation by a Telomeric Repeat

Jean-Louis Mergny, Jean-Claude Maurizot

Journal:

Year:

2001

Language:

english

File:

PDF, 178 KB

english, 2001

19

A Metal-Mediated Conformational Switch Controls G-Quadruplex Binding Affinity

David Monchaud, Peng Yang, Laurent Lacroix, Marie-Paule Teulade-Fichou, Jean-Louis Mergny

Journal:

Angewandte Chemie

Year:

2008

Language:

english

File:

PDF, 588 KB

english, 2008

20

Engineering Bisquinolinium/Thiazole Orange Conjugates for Fluorescent Sensing of G-Quadruplex DNA

Peng Yang, Anne De Cian, Marie-Paule Teulade-Fichou, Jean-Louis Mergny, David Monchaud

Journal:

Angewandte Chemie

Year:

2009

Language:

english

File:

PDF, 502 KB

english, 2009

21

A Metal-Mediated Conformational Switch Controls G-Quadruplex Binding Affinity

David Monchaud, Peng Yang, Laurent Lacroix, Marie-Paule Teulade-Fichou, Jean-Louis Mergny

Journal:

Angewandte Chemie International Edition

Year:

2008

Language:

english

File:

PDF, 589 KB

english, 2008

22

Engineering Bisquinolinium/Thiazole Orange Conjugates for Fluorescent Sensing of G-Quadruplex DNA

Peng Yang, Anne De Cian, Marie-Paule Teulade-Fichou, Jean-Louis Mergny, David Monchaud

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 502 KB

english, 2009

23

An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G-Quadruplex Topologies

Dr. Florian Hamon, Eric Largy, Aurore Guédin-Beaurepaire, Dr. Myriam Rouchon-Dagois, Assitan Sidibe, Dr. David Monchaud, Dr. Jean-Louis Mergny, Prof. Jean-Francois Riou, Dr. Chi-Hung Nguyen, Dr. Marie

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 407 KB

english, 2011

24

Telomerase: A Dimeric Ménage à Trois

Jean-Louis Mergny, Laurent Lacroix, Jean-François Riou

Journal:

Year:

2007

Language:

english

File:

PDF, 144 KB

english, 2007

25

Cooperative 2:1 Binding of a Bisphenothiazine to Duplex DNA

Frédéric Rosu, Valérie Gabelica, Edwin De Pauw, Patrick Mailliet, Jean-Louis Mergny

Journal:

Year:

2008

Language:

english

File:

PDF, 501 KB

english, 2008

26

Identification of Trinucleotide Repeat Ligands with a FRET Melting Assay

Samir Amrane, Anne De Cian, Frédéric Rosu, Markus Kaiser, Edwin De Pauw, Marie-Paule Teulade-Fichou, Jean-Louis Mergny

Journal:

Year:

2008

Language:

english

File:

PDF, 453 KB

english, 2008

27

G-Quadruplex Formation Interferes with P1 Helix Formation in the RNA Component of Telomerase hTERC

Julien Gros, Aurore Guédin, Jean-Louis Mergny, Laurent Lacroix

Journal:

Year:

2008

Language:

english

File:

PDF, 730 KB

english, 2008

28

Plasmodium Telomeric Sequences: Structure, Stability and Quadruplex Targeting by Small Compounds

Anne De Cian, Philippe Grellier, Elisabeth Mouray, Delphine Depoix, Hélène Bertrand, David Monchaud, Marie-Paule Teulade-Fichou, Jean-Louis Mergny, Patrizia Alberti

Journal:

Year:

2008

Language:

english

File:

PDF, 758 KB

english, 2008

29

Recognition of G-Quadruplex DNA by Triangular Star-Shaped Compounds: With or Without Side Chains?

Dr. Hélène Bertrand, Dr. Anton Granzhan, Dr. David Monchaud, Dr. Nicolas Saettel, Dr. Régis Guillot, Dr. Sarah Clifford, Aurore Guédin, Dr. Jean-Louis Mergny, Dr. Marie-Paule Teulade-Fichou

Journal:

Chemistry - A European Journal

Year:

2011

Language:

english

File:

PDF, 479 KB

english, 2011

30

Tridentate N-Donor Palladium(II) Complexes as Efficient Coordinating Quadruplex DNA Binders

Eric Largy, Dr. Florian Hamon, Dr. Frédéric Rosu, Dr. Valérie Gabelica, Prof. Edwin De Pauw, Aurore Guédin, Dr. Jean-Louis Mergny, Dr. Marie-Paule Teulade-Fichou

Journal:

Chemistry - A European Journal

Year:

2011

Language:

english

File:

PDF, 553 KB

english, 2011

31

G-Quadruplex Recognition by Quinacridines: a SAR, NMR, and Biological Study

Candide Hounsou, Lionel Guittat, David Monchaud, Muriel Jourdan, Nicolas Saettel, Jean-Louis Mergny, Marie-Paule Teulade-Fichou

Journal:

Year:

2007

Language:

english

File:

PDF, 516 KB

english, 2007

32

Telomerase Inhibition: Strategies and Protocols. Edited by Lucy G. Andrews and Trygve O. Tollefsbol.

Lionel Guittat, Jean-Louis Mergny

Journal:

Year:

2008

Language:

english

File:

PDF, 115 KB

english, 2008

33

2,6-Diphenylthiazolo[3,2-b][1,2,4]triazoles as telomeric G-quadruplex stabilizers

Jamal El Bakali, Frédérique Klupsch, Aurore Guédin, Bertrand Brassart, Gaëlle Fontaine, Amaury Farce, Pascal Roussel, Raymond Houssin, Jean-Luc Bernier, Philippe Chavatte, Jean-Louis Mergny, Jean-Fran

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 387 KB

english, 2009

34

Benzoindoloquinolines interact with DNA tetraplexes and inhibit telomerase

Patrizia Alberti, Philippe Schmitt, Chi-Hung Nguyen, Christian Rivalle, Magali Hoarau, David S. Grierson, Jean-Louis Mergny

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 144 KB

english, 2002

35

G-quadruplex DNA: A target for drug design

Mergny, Jean-Louis, Hélène, Claude

Journal:

Nature Medicine

Year:

1998

Language:

english

File:

PDF, 244 KB

english, 1998

36

Quartets in G-major. The First International Meeting on Quadruplex DNA

Bates, Paula, Mergny, Jean-Louis, Yang, Danzhou

Journal:

Year:

2007

Language:

english

File:

PDF, 536 KB

english, 2007

37

Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands

Pennarun, Gaëlle, Granotier, Christine, Gauthier, Laurent R, Gomez, Dennis, Hoffschir, Françoise, Mandine, Eliane, Riou, Jean-François, Mergny, Jean-Louis, Mailliet, Patrick, Boussin, François D

Journal:

Year:

2005

Language:

english

File:

PDF, 513 KB

english, 2005

38

Neomycin-capped aromatic platforms: quadruplex DNA recognition and telomerase inhibition

Kaiser, Markus, De Cian, Anne, Sainlos, Matthieu, Renner, Christian, Mergny, Jean-Louis, Teulade-Fichou, Marie-Paule

Journal:

Organic & Biomolecular Chemistry

Year:

2006

Language:

english

File:

PDF, 520 KB

english, 2006

39

FLUORESCENCE ENERGY TRANSFER BETWEEN DIMETHYLDIAZAPEROPYRENIUM DICATION AND ETHIDIUM INTERCALATED IN POLY d(A-T)

JEAN-LOUIS MERGNY, ANNY SLAMA-SCHWOK, THÉRÈSE MONTENAY-GARESTIER, MICHEL ROUGÉE, CLAUDE HÉLÈNE

Journal:

Photochemistry and Photobiology

Year:

1991

Language:

english

File:

PDF, 361 KB

english, 1991

40

Cationic Pentaheteroaryls as Selective G-Quadruplex Ligands by Solvent-Free Microwave-Assisted Synthesis

Michele Petenzi, Dr. Daniela Verga, Dr. Eric Largy, Dr. Florian Hamon, Dr. Filippo Doria, Dr. Marie-Paule Teulade-Fichou, Aurore Guédin, Dr. Jean-Louis Mergny, Prof. Mariella Mella, Prof. Mauro Frecce

Journal:

Chemistry - A European Journal

Year:

2012

Language:

english

File:

PDF, 729 KB

english, 2012

41

Pyrimidine Morpholino Oligonucleotides Form a Stable Triple Helix in the Absence of Magnesium Ions

Laurent Lacroix, Paola B. Arimondo, Masashi Takasugi, Claude Hélène, Jean-Louis Mergny

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 151 KB

english, 2000

42

Triple-Helix Specific Ligands StabilizeH-DNA Conformation

Guy Duval-Valentin, Thérèse de Bizemont, Masashi Takasugi, Jean-Louis Mergny, Emile Bisagni, Claude Hélène

Journal:

Journal of Molecular Biology

Year:

1995

Language:

english

File:

PDF, 953 KB

english, 1995

43

Energetics of strand-displacement reactions in triple helices: a spectroscopic study

Martin Mills, Paola B. Arimondo, Laurent Lacroix, Thérèse Garestier, Claude Hélène, Horst Klump, Jean-Louis Mergny

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 478 KB

english, 1999

44

Ultraviolet-A induces activation of AP-1 in cultured human keratinocytes

Mojgan Djavaheri-Mergny, Jean-Louis Mergny, France Bertrand, René Santus, Cécile Mazière, Louis Dubertret, Jean-Claude Mazière

Journal:

Year:

1996

Language:

english

File:

PDF, 682 KB

english, 1996

45

Label-free sensing of pH and silver nanoparticles using an “OR” logic gate

Dik-Lung Ma, Hong-Zhang He, Victor Pui-Yan Ma, Daniel Shiu-Hin Chan, Ka-Ho Leung, Hai-Jing Zhong, Lihua Lu, Jean-Louis Mergny, Chung-Hang Leung

Journal:

Analytica Chimica Acta

Year:

2012

Language:

english

File:

PDF, 592 KB

english, 2012

46

Targeting telomeres and telomerase

Anne De Cian, Laurent Lacroix, Céline Douarre, Nassima Temime-Smaali, Chantal Trentesaux, Jean-François Riou, Jean-Louis Mergny

Journal:

Year:

2008

Language:

english

File:

PDF, 1.78 MB

english, 2008

47

Sequence effects in single-base loops for quadruplexes

Aurore Guédin, Anne De Cian, Julien Gros, Laurent Lacroix, Jean-Louis Mergny

Journal:

Year:

2008

Language:

english

File:

PDF, 1.40 MB

english, 2008

48

Targeting DNA

Jonathan B. Chaires, Jean-Louis Mergny

Journal:

Year:

2008

Language:

english

File:

PDF, 98 KB

english, 2008

49

Meeting report: Guanosines and quadruplexes (London, September 15–17, 2010)

Jean-Louis Mergny, Anne Bourdoncle, Lea Spindler

Journal:

Year:

2011

Language:

english

File:

PDF, 430 KB

english, 2011

50

Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes

Phong Lan Thao Tran, Antonella Virgilio, Veronica Esposito, Giuseppe Citarella, Jean-Louis Mergny, Aldo Galeone

Journal:

Year:

2011

Language:

english

File:

PDF, 978 KB

english, 2011

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